CYP450 Inhibition Assays
- Microsomes with recombinant baculovirus containing cDNA for individual human cytochrome P450 (CYP450) enzymes
- Major CYP450 isozymes: 1A2, 2C9, 2C19, 2D6, 3A4
CYP450 Phenotyping Assays
- To determine the actual cytochrome P450 (CYP450) responsible for the metabolism
- Cross-species phenotyping assay
- Metabolite identification