PHARMACOKINETICS
Pharmidex provides translational solutions in state-of-the-art facilities in Hertfordshire, UK. We have extensive knowledge of drug discovery and development. We offer high-quality, tailored pharmacokinetic services, critical to the progression of your drug discovery programme.
Key Services
- Bespoke protocol designs available to fit project needs with experienced scientific liaisons assigned to support
- Fully integrated in vivo/bioanalysis/PK parameter determination
- Multiple routes of dose administration available, including specialised routes (please enquire)
- Pharmacokinetic profiling in a range of pre-clinical species (single and repeat dose)
- Samples can also be shipped on behalf of sponsor
- Short lead times and rapid delivery of in vivo studies
- Surgical models available in-house, including serial bile collection in Bile Duct Catheterised (BDC) species
- AAALAC accredited and IACUC/OLAW approved
- Collection of multiple tissue samples for drug distribution studies
- CSF collection in multiple pre-clinical species
- In Situ BBB permeability and efflux transporter assessment
- Metabolic cages for clearance assessment in urine/faeces
- PK scaling to humans / human dose prediction and efflux transporter assessment
- Specialist models for CNS including microdialysis (for more info, visit our
CNS
service page)
