DRUG METABOLISM
Primarily using UHPLC - high resolution / accurate mass spectrometry, Pharmidex scientists can carry out studies of drug metabolism.
Our highly experienced team can help to resolve issues with high clearance, characterise metabolite profiles across species, and investigate potential reactive metabolism liabilities.
Bioanalysis Service
Pharmidex has considerable experience in the design, conduct and analysis of samples from
in vitro and
in vivo drug metabolism studies, offering a tailored approach to suit client needs.
Areas of Expertise
- Assistance with optimising study design
- Cross-species metabolite profiling
- Identification of metabolically labile sites
- Identification of potential sites of reactive metabolism
- Structural characterisation of metabolites