๐Ÿ”ฌ Now at Pharmidex: The 8HUM Model
July 21, 2025

Pharmidex is proud to offer access to the 8HUM model genetically humanized for 33 liver CYP enzymes responsible for metabolizing 90% of human drugs.


โœ… Human-relevant metabolism data

โœ… Supports IND-enabling & regulatory studies

โœ… Ideal for metabolite profiling, DDI risk & toxicity assessment


By integrating 8HUM into our DMPK and in vivo studies, we deliver deeper, more predictive insights for safer, smarter drug development.


๐Ÿ“ฉ Contact us to see how 8HUM can support your project.


#Pharmidex #8HUM #DrugMetabolism #DMPK #PreclinicalResearch #InVivoPharmacology #DrugDevelopment

July 17, 2025
We’re growing and looking for passionate scientists to join our dynamic team. If you're excited by impactful science and meaningful collaboration, check out our latest roles: ๐Ÿ”ฌ Bioanalytical Scientist (Permanent) Work with LC-MS/MS platforms to support preclinical and clinical bioanalysis across a wide range of therapeutic areas. ๐Ÿงซ Histology Technician (3-Month FTC, Full or Part-Time) Be at the heart of tissue processing for in vivo and toxicology studies GLP experience welcome, flexibility offered. ๐Ÿงช Scientist / Senior Scientist – Immunology (Full-Time) Advance autoimmune disease research through innovative T-cell and cytokine profiling assays. ๐Ÿ’ก Why Pharmidex? โœ” 20+ years of scientific excellence โœ” Collaborative, science-led culture โœ” Diverse therapeutic expertise โœ” Real-world impact through discovery and development ๐Ÿ“ฉ Ready to apply or want to learn more? Visit www.pharmidex.com/careers or email your CV to [email protected] Applications are reviewed on a rolling basis, early interest encouraged! ๏ปฟ Let’s shape the future of drug discovery together.
July 15, 2025
We’re excited to introduce our GLP-standard intracranial dosing platform delivering targeted compounds directly to the brain for more precise CNS preclinical studies. โœ… Bypasses the blood-brain barrier โœ… Reduces systemic side effects โœ… Enhances translational relevance Now fully GLP-validated with: Documented SOPs & equipment Verified dose placement MHRA-audited compliance ๐Ÿ“ˆ Benefits: Regulatory-ready data, better reproducibility, and lower repeat study costs. ๐Ÿ‘‰ Swipe the carousel to learn more. ๐Ÿ”— www.pharmidex.com
New Insights from Pharmidex: Tumour Microdialysis in Glioblastoma
July 10, 2025
We’re excited to share our latest work on tumour microdialysis, a powerful technique for measuring unbound, pharmacologically active drug concentrations directly within brain tumours like glioblastoma. Unlike systemic plasma levels, microdialysis provides a true picture of drug penetration into the tumour helping to uncover heterogeneous distribution and the impact of the blood-tumour barrier. Our approach involves precise stereotaxic surgery, tumour validation, and sampling from both tumour and healthy brain tissue enabling direct, comparative pharmacokinetic analysis. ๐Ÿ“Š The results? Significant differences in drug exposure between tumour core and surrounding tissue. ๐Ÿ‘‰ Swipe through the carousel to explore our process and findings. ๏ปฟ ๐Ÿ”— www.pharmidex.com
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