DRUG METABOLISM SERVICE

Primarily using UHPLC - high resolution / accurate mass spectrometry, Pharmidex scientists can carry out studies of drug metabolism. Our highly experienced team can help to resolve issues with high clearance, characterise metabolite profiles across species, and investigate potential reactive metabolism liabilities.

Bioanalysis Service

Pharmidex has considerable experience in the design, conduct and analysis of samples from in vitro and in vivo drug metabolism studies, offering a tailored approach to suit client needs.

Areas of Expertise

  • Identification of metabolically labile sites
  • Cross-species metabolite profiling
  • Structural characterisation of metabolites
  • Identification of potential sites of reactive metabolism
  • Assistance with optimising study design
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