PHARMACOKINETICS


Pharmidex provides translational solutions in state-of-the-art facilities in Hertfordshire, UK. We have extensive knowledge of drug discovery and development. We offer high-quality, tailored pharmacokinetic services, critical to the progression of your drug discovery programme.

Key Services

  • Fully integrated in vivo/bioanalysis/PK parameter determination
  • Samples can also be shipped on behalf of sponsor
  • Short lead times and rapid delivery of in vivo studies
  • Bespoke protocol designs available to fit project needs with experienced scientific liaisons assigned to support
  • Pharmacokinetic profiling in a range of pre-clinical species (single and repeat dose)
  • Multiple routes of dose administration available, including specialised routes (please enquire)
  • Surgical models available in-house, including serial bile collection in Bile Duct Catheterised (BDC) species
  • Collection of multiple tissue samples for drug distribution studies 
  • Metabolic cages for clearance assessment in urine/faeces
  • CSF collection in multiple pre-clinical species
  • In Situ BBB permeability and efflux transporter assessment
  • AAALAC accredited and IACUC/OLAW approved
  • PK scaling to humans / human dose prediction and efflux transporter assessment
  • Specialist models for CNS including microdialysis (for more info, visit our          service page)
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